Other side effects include a drop in blood pressure, insomnia, nasal congestion, or a runny nose and nosebleeds.Dyspepsia, flushing, headache, indigestion, muscle or back pain, and visual disturbances are commonly reported.If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: There is also a generic version of Viagra available, under the name sildenafil, in 25mg, 50mg, and 100mg strengths. Revatio is available as a generic under the name of sildenafil (20mg tablet).Available orally and as an IV preparation for PAH.This improves the ability to exercise in people with PAH and delays any worsening of their symptoms. Sildenafil (Revatio brand) reduces high blood pressure associated with pulmonary arterial hypertension (PAH). It works within 30 to 60 minutes, but may be taken up to four hours before sexual activity. Sildenafil (Viagra brand) only works following sexual stimulation.This allows men to keep an erection hard enough for sex. cGMP is a substance that relaxes and widens blood vessels and smooth muscle cells. It does this by blocking the enzyme responsible for the breakdown of cGMP. Sildenafil (Viagra brand) increases blood flow to the penis following sexual stimulation.Sildenafil belongs to the class of medicines known as selective phosphodiesterase (PDE) type 5 inhibitors.PDE-5 is also found throughout the body within the smooth muscle cells of the blood vessels and muscles. High levels of PDE-5 are found in the penis, lungs, and retina.Blocking PDE-5 means increased levels of cGMP within the smooth muscles which promotes muscle relaxation and vasodilation (a widening of blood vessels). This enzyme breaks down cGMP, a substance that induces smooth muscles to relax. Sildenafil blocks the action of an enzyme known as cGMP-specific phosphodiesterase type-5 (PDE-5).Sildenafil may be used to treat erectile dysfunction (ED or impotence) in men (Viagra brand) or pulmonary arterial hypertension in both men and women (Revatio brand), depending on the brand.Medically reviewed by Carmen Pope, BPharm.
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